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Insights Archive

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DRUG SPOTLIGHT Cytisinicline

Cytisinicline is an emerging smoking cessation therapy that has demonstrated strong quit rates and favorable tolerability in clinical trials, positioning it as a promising new option for individuals looking to overcome nicotine dependence.

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A New Look, The Same Trusted Commitment

What began as a mission-driven alternative to traditional PBMs has grown into a trusted partner for organizations across the country. As ClearScript has evolved, so has our vision for the...

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A generic bottle spilling red and white pills onto a wood counter. A gavel sits beside the bottle.

PBM reform is here.

ClearScript remains committed to transparency. For plan sponsors, recent federal reforms mean PBM decisions should be easier to understand and…

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DRUG SPOTLIGHT Foundayo (orforglipron)

Foundayo is approved for use in combination with a reduced-calorie diet and increased physical activity to reduce excess body weight and maintain weight reduction long term in adults…

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DRUG SPOTLIGHT Wegovy Tablets (semaglutide)

Manufacturer Novo Nordisk received FDA approval for oral semiglutide on 12/22/2025. These new indications for Wegovy tablets are for chronic weight management and to reduce the risk of major cardiovascular events in adults with obesity or overweight.

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Compliance and Industry Update – November 2025

At ClearScript, we are committed to keeping you informed and prepared for the evolving landscape of Pharmacy Benefit Management (PBM). This update highlights key regulatory changes, industry updates, and ClearScript’s proactive strategies.

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Your Guide to Managing Trend in 2026

If you’re managing pharmacy benefits in 2026, you’re likely facing rising costs, new therapies, and tough decisions. So how do you stay ahead? It starts with understanding what drives trend and how to manage it with confidence.

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ADHD medications and Scrabble tiles spelling ADHD

DRUG SPOTLIGHT: Centanafadine

Centanafadine is a novel, first-in-class, non-stimulant under development for the treatment of attention-deficit/hyperactivity disorder (ADHD) in children, adolescents, and adults.  It’s rapid onset & good safety profile would likely result in uptake for patients who do not respond to generic stimulant / non-stimulant therapy options.

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